Mendelspod

Spatial Transcriptomics Is Changing How We Do Biology: Fei Chen, The Broad Institute

Fei Chen of the Broad Institute describes the original problem simply: genomics gave us powerful inventories of gene expression, while microscopy gave…

Apr 9 • Theral Timpson

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31:42

Beyond GLP-1: Why Peptides Are Back at the Center of Drug Discovery with Charlie Johannes and Tomi Sawyer

Peptides are having a moment.

Apr 7 • Theral Timpson

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44:06

From the Archives: Inventor Mark Kokoris Debuts Roche’s New SBX Sequencer

It was the biggest story in sequencing last year: Mark Kokoris, head of SBX sequencing at Roche and inventor of the technology, joins Mendelspod to talk…

Apr 2 • Theral Timpson

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35:51

March 2026

Why Do Some Animals Live Ten Times Longer? Pursuing the Science of Aging with Steve Austad

Why do some animals live ten times longer than others?

Mar 17 • Theral Timpson

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38:22

MRD Testing: From Residual Disease to Real Decisions with Chris Hourigan and Gary Pestano

Molecular residual disease, or MRD, has been part of oncology’s vocabulary for decades.

Mar 10 • Theral Timpson

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33:32

Early vs Late Recurrence: How Multimodal AI Is Changing Breast Cancer Prognosis with George Sledge, Caris Life Sciences

For two decades, tests like Oncotype DX have helped oncologists decide which early-stage breast cancer patients should receive chemotherapy.

Mar 5 • Theral Timpson

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35:02

The Dark Genome with Author Sudhakaran Prabakaran

We began this podcast back around the time the ENCODE project announced that much of the genome was biochemically active.

Mar 3 • Theral Timpson

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37:16

February 2026

Illumina's New Mapped Read Technology Provides Insights into Rare Disease: Stephen Kingsmore, Olivia Kim-McManus and Ali Crawford

From diagnostic to therapeutic odyssey

Feb 26 • Theral Timpson

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27:14

CareDx’s Second Act with CEO John Hanna

CareDx is a company on the move.

Feb 17 • Theral Timpson

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37:55

Inside GP2: Building a Global Genetic Map of Parkinson’s with Andrew Singleton and Ignacio Mata

Large-scale genomics is back.

Feb 10 • Theral Timpson

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40:44

A Simple Sponge, a Big Shift in Cell Therapy with Yev Brudno, UNC

What if the hardest part of scaling cell therapy turned out to be a materials problem not a biological one—and the solution looked like a sponge?

Feb 3 • Theral Timpson

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30:39

January 2026

How Cellanome Is Changing the Way We Study Cell Function with Matthew Spitzer and Pier Federico Gherardini

For today’s show, we return to discussing the exciting new Cellanome platform.

Jan 29 • Theral Timpson

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23:56